Glock 21 Gen5 MOS .45ACP 10-Round Pistol
The Glock 21 Gen5 MOS .45ACP brings big-bore power into the latest generation of Glock innovation. Built with a 10-round capacity, this full-size pistol delivers the stopping power of .45 Auto with the performance and features you’d expect from the Gen5 series.
The G21 Gen5 features Glock’s Modular Optic System (MOS), allowing you to easily mount a red dot sight using a variety of adapter plates. Paired with front and rear slide serrations, the slide is easy to grip and manipulate, even with gloves or in wet conditions.
Underneath, the nDLC-finished slide and barrel resist wear, corrosion, and scratches. The Glock Marksman Barrel (GMB) improves accuracy with tighter tolerances and a smoother bore. The pistol also drops the finger grooves for a more ergonomic grip and includes interchangeable backstraps to fit your hand perfectly.
Like all Gen5 Glocks, the G21 includes an ambidextrous slide stop lever, a flared magwell for faster reloads, and Glock’s Safe Action® System for consistent performance and trusted safety.
Whether you’re using it for duty, defense, or range time, the Glock 21 Gen5 MOS .45ACP is a powerhouse you can depend on.
Why the Glock 21 Gen5 MOS stands out:
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MOS-ready slide for red dot optics
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Chambered in powerful .45ACP with a 10+1 capacity
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Gen5 features: flared magwell, no finger grooves, GMB barrel
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Durable nDLC slide and barrel finish
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Ambidextrous slide stop lever
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Interchangeable backstraps for a custom grip
Specs at a Glance:
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Caliber: .45 Auto
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Capacity: 10+1
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Barrel Length: 4.61 inches
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Action: Striker-fired
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Frame: Black polymer (Gen5 design)
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Slide: nDLC finish, optics-ready (MOS)
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Sights: Fixed Glock sights
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Overall Length: 8.07 inches
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Weight (unloaded): Approx. 29.3 oz
FAQ
Q: Can I mount a red dot on the G21 Gen5 MOS?
A: Yes. It includes the MOS system to mount most major red dot optics with adapter plates.
Q: Is this a good choice for home defense?
A: Absolutely. The .45ACP chambering and Gen5 reliability make it ideal for serious defense.
Q: What magazines work with this model?
A: It uses Glock factory 10-round .45ACP magazines, perfect for compliant states or backup carry.






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